2023
Feng, W.W., Bang, S., Takacs, E.M., Day, C., Crawford, K.J., Al-Sheyab, R., Almufarrej, D.B., Wells, W., Ilchenko, S., Kasumov, T., Kon, N., Novak, C.M., Gu, W., Kurokawa, M. Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring. iScience 26, 108405.
Feng, W.W. Zuppe, H.T., Kurokawa, M. Regulation of CD36 Expression and Activity in Cancer Scholary Community Encyclopedia
Feng, W.W. Zuppe, H.T., Kurokawa, M. The role of CD36 in cancer progression and its value as a therapeutic target. Cells 12, 1605.
Kaur, S., Kurokawa, M. Regulation of Oocyte Apoptosis: A View from Gene Knockout Mice. 2023. International Journal of Molecular Sciences 24, 1345. In Special Issue: Stress Signalling and Programmed Cell Death
2022
Pennington KL, McEwan CM, Woods J, Muir C, Sahankumari AGP, Eastmond R, Balasooriya ER, Egbert CM, Kaur S, Heaton T, McCormack KK, Piccolo SR, Kurokawa M, Andersen JL. 2022. SGK2, 14-3-3 and HUWE1 cooperate to control the localization, stability and function of the oncoprotein PTOV1. Molecular Cancer Research 20, 231–243.
Schaafsma, E., Eric T., Kaur, S., Cheng, C., Kurokawa, M. 2022. Predicting clinical outcomes of cancer patients with a p53 deficiency gene signature. Scientific Reports 12, 1317.
2021
Eisa A, Dey S, Ignatious A, Nofal W, Hess RA, Kurokawa M, Kline D, Vijayaraghavan S. 2021. The protein YWHAE (14-3-3 epsilon) in sperm is essential for male fertility. Andrology 9, 312-328.
Model MA, Hollembeak J, Kurokawa M. 2021. Macromolecular crowding: a hidden link between cell volume and everything else. Cellular Physiology and Biochemistry 55(S1), 25-40. In Special Issue: Mechanisms and Functional Significance of Cell Volume Regulation
2020
Eisa A.A., Bang, S., Crawford, K.J., Murphy, E.M., Feng, W.W., Dey, S., Wells, W., Kon, N., Gu, W., Mehlmann, L.M., Vijayaraghavan, S., Kurokawa, M. 2020. X-linked Huwe1 is essential for oocyte maturation and preimplantation embryo development. iScience 23, 101523.
Jayawardhana, A.M.D.S., Stilgenbauer, M., Datta, P., Qiu, Z., Mckenzie, S., Wang, H., Bowers, D., Kurokawa, M., Zheng, Y. 2020. Fatty acid-like Pt(IV) prodrugs overcome cisplatin resistance in ovarian cancer by harnessing CD36. Chemical Communications 56, 10706-10709.
Datta,P., Bang, S., Yue, Z., Beach, T., Sabrina, A., Wang, H., Bowers, D.J., Kurakawa, M., Xiao, H., and Zheng Y. 2020. Engineering liposomal nanoparticles of cholesterol-tethered amphiphilic Pt(IV) prodrugs with prolonged circulation time in blood. Dalton Transactions 49, 8107-8113.
Rana, P.S., Kurokawa, M., Model, M.A. 2020. Evidence for macromolecular crowding as a direct apoptotic stimulus. Journal of Cell Science 133, jcs243931.
Feng, W.W., Kurokawa, M. 2020. Lipid metabolic reprogramming as an emerging mechanism of resistance to kinase inhibitors in breast cancer. Cancer Drug Resistance 3, 1-17. In Special Issue: Promises and Pitfalls of Kinase Inhibitors as Therapeutics for Cancer Resistance
Cassidy, K.B.*, Bang, S.*, Kurokawa, M.**, Gerber, S.A.** 2020. Direct regulation of Chk1 protein stability by E3 ubiquitin ligase HUWE1. The FEBS Journal 287, 1985-1999 (Editor’s Choice). * co-first authors, ** co-corresponding authors Comments in Regulation of CHK1 by the Ubiquitin–Proteasome System (FEBS J, 2020. 287, 1982-1984)
Feng, W.W., Bang, S., Kurokawa, M. 2020. CD36: a key mediator of resistance to HER2 inhibitors in breast cancer. Molecular & Cellular Oncology 7, 1715766.
Bang, S., Kaur, S., Kurokawa, M. 2020. Regulation of the p53 family proteins by the ubiquitin proteasomal pathway. International Journal of Molecular Sciences 21, 216. In Special Issue: p53 in Cancer and beyond—40 Years after Its Discovery
Will’s JRNLclub debut!
14’56”! He nailed it!!
Image by Cooper Liedtke.
2019
Feng, W.W., Wilkins, O.M., Bang, S., Ung, M., Li, J. , An, J., del Genio, C.L., Canfield, K., DiRenzo, J., Wells, W., Gaur, A., Robey, R.B., Guo J.Y., Powles, R.L., Sotiriou, C., Pusztal L., Febbraio, M., Cheng, C., Kinlaw, W.B., Kurokawa, M. 2019. CD36-mediated metabolic rewiring of breast cancer cells promotes resistance to HER2-targeted therapies. Cell Reports 29, 3405–3420.
2018
Bang, S., Bhatt H.C., Chen Y.Y., Kurokawa, M. 2018. MDM2. In: Choi, S (ed). Encyclopedia of Signaling Molecules Second Edition, Volume 5, 3021-3028. Springer.
Huang A., Yang, E., Kurokawa, M. 2018. MDM4 (MDMX). In: Choi, S (ed). Encyclopedia of Signaling Molecules Second Edition, Volume 5, 3028-3034. Springer.
2017
Deming P.B. Kurokawa, M. 2017. Dismantling the apoptotic cells by caspases. In: Melino, G (ed). Encyclopedia of Life Sciences (eLS) 1-10. John Wiley & Sons.
2016
Matsuura, K., Canfield, K., Feng W., Kurokawa, M. 2016. Metabolic regulation of apoptosis in cancer. International Review of Cell & Molecular Biology 327, 43-87.
Canfield, K., Wells, W., Geradts, J., Kinlaw, W.B., Cheng, C., Kurokawa, M. 2016. Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma. International Journal of Clinical and Experimental Pathology 9, 6342-6349.
2015
Li, J., Kurokawa, M. 2015. Regulation of MDM2 stability after DNA damage. Journal of Cellular Physiology 230, 2318–2327.
Canfield, K., Li, J., Wilkins, O.M., Morrison M.M., Ung, M., Wells, W., Williams, C.R., Liby, K.T., Vullhorst, D., Buonanno, A., Schiff, R., Cook, R.S., Kurokawa, M. 2015. ERBB4 tyrosine kinase mediates acquired resistance to ERBB2 inhibitors in breast cancer cells. Cell Cycle 14, 648-655. Comments in Erbb4 Signaling: an overlooked backup system? (Cell Cycle, 2015)
2013
Fernald, K., Kurokawa, M. 2013. Evading apoptosis in cancer. Trends in Cell Biology 23, 620-633.
McCoy, F., Darbandi, R., Lee, H.C., Bharatham, K., Moldoveanu, M., Royappa, G., Dodd, K., Lin, W., Chen, S.I., Tangallapally, R.P., Kurokawa, M., Lee, R.E., Shelat, A., Chen, T., Green, D.R., Harris, R.A., Lin, S.H., Fissore, R.A., Colbran, R.J., Nutt, L.K. 2013. Metabolic activation of CaMKII by Coenzyme A. Molecular Cell 52, 325-339.
Kurokawa, M., Kim, J., Geradts, J., Matsuura, K., Liu, L., Xia, W., Ribar, T.J., Dewhirst, M.W., Kim, W.-J., Wang, S., Spector, N.L., Kornbluth, S. 2013. A network of substrates of the E3 ligases MDM2 and HUWE1 control apoptosis independently of p53. Science Signaling 6, Ra32.
Kurokawa, M., Ito, T., Yang, C.S., Zhao, C., Macintyre, A.N., Rizzieri, D.A., Rathmell, J.C., Deininger, M.W., Reya, T., Kornbluth, S. 2013. Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells. Proceedings of the National Academy of Sciences 110, 2300-2305.
2012
Kim, J., Parrish, A.B., Kurokawa, M., Matsuura, K., Freel, C.D., Andersen, J.L., Johnson, C.E., Kornbluth, S. 2012. Rsk-mediated phosphorylation and 14-3-3ε binding of Apaf-1 suppresses cytochrome c-induced apoptosis. EMBO Journal 13, 1279-1292.
2010
Kurokawa, M., Kornbluth, S. 2010. Stalling in mitosis and releasing the apoptotic brake. EMBO Journal 29, 2255-2257.
2009
Kurokawa, M., Kornbluth, S. 2009. Caspases and kinases in a death grip. Cell 138, 838-854.
Nutt, L.K., Buchakjian, M.R., Gan, E., Darbandi, R., Yoon, S.Y., Wu, J.Q., Miyamoto, Y.J., Gibbon, J.A., Andersen, J.L., Freel, C.D., Tang, W., He, C., Kurokawa, M., Wang, Y., Margolis, S.S., Fissore, R.A., Kornbluth, S. 2009. Metabolic control of oocyte apoptosis mediated by 14-3-3-regulated dephosphorylation of caspase-2. Developmental Cell 16, 856-866.
2008
Kurokawa, M., Zhao, C., Reya, T., Kornbluth, S. 2008. Inhibition of apoptosome formation by suppression of Hsp90β phosphorylation in tyrosine kinase-induced leukemias. Molecular and Cellular Biology 28, 5494-5506.
2007
Kurokawa, M., Yoon, S.-Y., Alfandari, D., Fukami, K., Sato, K.-I., Fissore, R.A. 2007. Proteolytic processing of phospholipase Cζ and [Ca2+]i oscillations during mammalian fertilization. Developmental Biology 312, 407-418.
Wortzman-Show, G.B., Kurokawa, M., Fissore, R.A., Evans, J.P. 2007. Calcium and sperm components in the establishment of the membrane block to polyspermy: studies of intracytoplasmic sperm injection (ICSI) and activation with sperm factor. Molecular Human Reproduction 13, 557-565.
Markoulaki, S., Kurokawa, M., Yoon, S.-Y.,* Matson, S., Ducibella, T., Fissore, R. 2007. Comparison of Ca2+ and CaMKII responses in IVF and ICSI in the mouse. Molecular Human Reproduction 13, 265-272.
Villemure, M., Chen, H.-Y., Kurokawa, M., Fissore, R.A., Taketo, T. 2007. The presence of X- and Y-chromosomes in oocytes results in impairment of the second meiotic division. Developmental Biology 301, 1-13.
2006
Malcuit, C., Kurokawa, M., Fissore, R.A. 2006. Calcium oscillations and mammalian egg activation. Journal of Cellular physiology 206, 565-573.
2005
Kurokawa, M., Sato, K.-I., Wu, H., He, C., Malcuit, C., Black, S.J., Fukami, K., Fissore, R.A. 2005. Functional, biochemical, and chromatographic characterization of the complete [Ca2+]i oscillation-inducing activity of porcine sperm. Developmental Biology 285, 376-392.
Knott, J.G., Kurokawa, M., Fissore, R.A., Schultz, R.M., Williams, C.J. 2005. Transgenic RNA interference (RNAi) reveals role for mouse sperm phospholipase Cζ in triggering Ca2+ oscillations during fertilization. Biology of Reproduction 72, 992-996.
2004
Sato, K.-I., Sette, C., Kurokawa, M., Paronetto, M.P., Iwasaki, T., Fissore, R.A., Fukami, Y. 2004. Fertilizome project: Proteomics of fertilization signaling, the biological bridge between gametogenesis and embryogenesis. Current Proteomics 1, 231-246.
Kurokawa, M., Sato, K.-I., Fissore, R.A. 2004. Mammalian fertilization: from sperm factor to phospholipaseζ. Biology of the Cell 96, 37-45.
Jellerette, T., Kurokawa, M., Lee, B., Malcuit, C. Yoon, S.Y., Smyth, J., Vermassen, E., De Smedt, H., Parys, J.B., Fissore, R.A. 2004. Cell cycle-coupled [Ca2+]i oscillations in mouse zygotes and function of the inositol 1,4,5-trisphosphate receptor-1. Developmental Biology 274, 94-109.
Kurokawa, M., Sato, K.-I., Smyth, J., Wu, H., Fukami, K., Takenawa, T., Fissore, R.A. 2004. Evidence that activation of a Src family kinase is not required for fertilization-associated [Ca2+]i oscillations in mouse eggs. Reproduction 127, 441-454.
Bedford, S.J., Kurokawa, M., Hinrichs, K., Fissore, R.A. 2004. Patterns of intracellular calcium oscillations in horse oocytes fertilized by intracytoplasmic sperm injection: possible explanations for the low success of this assisted reproduction technique in the horse. Biology of Reproduction 70, 936-944.
2003
Fukami, K., Inoue, T., Kurokawa, M., Fissore, R.A., Nakao, K., Nagano, K., Nakamura, Y., Takenaka, K., Yoshida, N., Mikoshiba, K., Takenawa, T. 2003. Phospholipase Cδ4: from genome structure to physiological function. Advances in Enzyme Regulation 43, 87-106.
Sato, K.-I., Tokmakov, A.A., He, C.-L., Kurokawa, M., Iwasaki, T., Shirouzu, M., Fissore, R.A., Yokoyama, S., Fukami, Y. 2003. Reconstitution of Src-dependent PLCγ phosphorylation and transient calcium release by using membrane rafts and cell-free extracts from Xenopus eggs. Journal of Biological Chemistry 278, 38413-38420.
Bedford, S.J., Kurokawa, M., Hinrichs,, K., Fissore, R.A. 2003. Horse oocytes display calcium transients when microinjected with equine sperm extracts. Reproduction 126, 489-499.
Knott, J.G., Kurokawa, M., Fissore, R.A. 2003. Release of the Ca2+ oscillation-inducing sperm factor during mouse fertilization. Developmental Biology 260, 536-547.
Kurokawa, M., Fissore, R.A. 2003. Intracytoplasmic sperm injection (ICSI)-generated embryos exhibit altered [Ca2+]i oscillations, IP3R-1 down-regulation, and embryonic development. Molecular Human Reproduction 9, 523-533.
Fukami, K., Yoshida, M., Inoue, T., Kurokawa, M., Fissore, R.A., Yoshida, N., Mikoshiba, K., Takenawa, T. 2003. Phospholipase Cδ4 is required for Ca2+-mobilization essential for acrosome reaction in sperm. Journal of Cell Biology 161, 79-88.
2002
Gordo, A.C., Kurokawa, M., Wu, H., Fissore, R.A. 2002. Modification of the Ca2+ release mechanisms of mouse oocytes by fertilization and by sperm factor. Molecular Human Reproduction 8, 619-629.
Gordo, A.C., Rodrigues, P.,Kurokawa, M., Jullerette, T., Fissore, R.A. 2002. [Ca2+]i oscillations signal apoptosis rather than activation in in vitro aged mouse eggs. Biology of Reproduction 66, 1828-1837.
Fissore, R.A., Kurokawa, M., Knott, J., Zhang, M., Smyth, J. 2002. Mechanisms underlying oocyte activation and postovulatory ageing. Reproduction 124, 745-754.
Fissore, R.A., Smyth, J., Kurokawa, M., Collas, P. 2002. Activation of mammalian oocyte. In: Principles of Cloning Cibelli, J., Campbell, K., Lanza, R., West, M. (Eds.), Academic Press, pp. 21-45.
2001
Fukami, K., Nakao, K., Inoue, T., Kataoka, Y., Kurokawa, M., Fissore, R.A., Nakamura, K., Katsuki, M., Mikoshiba, K., Yoshida, N., Takenawa, T. 2001. Requirement of phospholipase Cδ4 for zona pellucida-induced acrosome reaction. Science 292, 920-923.